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学術論文

Veterin Ther 2001 ; 2(2) : 101-11

Influence of Green Lipped Mussels (Perna canaliculus) in Alleviating Signs of Arthritis in Dogs

Bui LM, Bierer TL.

関節炎のイヌ31頭を対象に、適切な管理のもと無作為二重盲検試験を実施しました。イヌは通常の乾燥ドッグフード群と緑イ貝抽出物添加乾燥ドッグフード群に無作為に分類され、獣医師は痛み、腫脹、関節摩擦音、可動領域の減少の程度に基づき、各イヌの関節炎重症度をスコア化しました。6週間後、コントロール群と比較し、緑イ貝抽出物投与群において関節炎のスコアの有意な改善が認められ、特に、痛み、腫脹において著しい変化が認められました。

Abstract

This study evaluated the efficacy of green lipped mussel (GLM), added to a complete dry diet, for alleviating clinical signs of arthritis in dogs. A double-blind longitudinal study design was used with 31 mixed-breed dogs exhibiting varying degrees of arthritis. Each dog was evaluated by a veterinarian and joints were individually scored for degree of pain, swelling, crepitus, and reduction in range of movement. Summation of all scores for an individual dog comprised its total arthritis score. At baseline, dogs were randomly allocated to control and test groups. Both groups were fed the same base dry diet, to which 0.3% GLM powder was added for dogs in the test group. The change in total arthritis score by the end of 6 weeks showed there was significant improvement (P < .05) in the test group versus the control group. Significant improvements were also observed in joint pain and swelling scores in the test group. Changes in joint crepitus and range of joint movement were not significantly different between the test and control groups. These findings provide strong evidence that GLM incorporated into a complete dry diet can help alleviate arthritis symptoms in dogs.